Influence of Ecotoxicants on Immune System of the Aral Sea Region People’s Health

The Aral Sea problem, as the largest environmental disaster in the world, has acquired an acute character. Intense desertification, sustainable irreversible degradation of the environment and deterioration of living conditions caused an increased incidence of new socio-economic and environmental situations that require legislative solutions and legal regulation of social protection of the population living in ecologically unfavorable areas. To assess the immune status used standard immunoassay method for the determination of immunoglobulin A, M, G, E. on the results of the study we found that the content of the class IgE women zone eco-catastrophe in all age groups were significantly lower than in women zone of ecological crisis, while male the zone of ecological disaster, on the contrary, there was increased concentration of it, especially in the young and the oldest age groups, in which the figure reached a peak (At mean values) in excess of the normal levels, which may constitute a risk of formation, in the future of allergy. The concentration of IgG, M level in men environmental crisis zone was higher than that of similar groups in the zone of ecological disaster, which indicates the probability of a large environmentally induced immunological stress the population of the area adjacent to Aral. At the same time, the analysis of the frequency of pathologically reduced content of IgM, G in males and female’s zone eco-disaster set its highest frequency, compared to the population of eco-zone crisis.